Integrative Analysis of 16S and ITS
Based on the advanced technology platform, Creative Proteomics provides 16S and ITS sequencing services and integrated analysis services of 16S-ITS. We can provide you with a one-stop service from experimental design, sample detection, independent omics data analysis to integrative analysis to meet a variety of research needs.
Why Do Integrative Analysis of 16S and ITS?
Due to differences in ecological niches, bacteria and fungi respond differently to environmental stimuli, etc. There are also certain interactions between bacteria and fungi due to possible substrate competition, secretion of antibiotics, etc. Some studies have shown that between 16S / ITS and 18S, 16S and ITS are the most correlated, implying a strong association between fungi and bacteria.
Our Integrative Analysis Services of 16S and ITS
Creative Proteomics provides you with one-stop 16S and ITS sequencing services. In addition, we provide comprehensive analysis services for 16S and ITS, seamlessly connecting your experiments to provide powerful insights into the evidence of complex microbial activity mechanisms.
Bioinformatics Analysis
| Analysis content |
Analysis purpose |
Visualisation diagram |
| Beta diversity correlation analysis |
We performed statistical tests for within / between group distance differences based on the distance means of the samples within / between groups for each comparison group and combined them into a single graph. The graphs can be used to directly compare whether there are similar patterns in the response / drive of bacteria and fungi to phenotypic differences. For example it may be that group differences only affect bacteria, or both. |
Combined distance box plots
Mantel test scatter plot
Procrustes test scatter plot |
| Species association analysis |
The combination shows the species distribution of bacteria and fungi, dominant species, trends and other information. |
Bacteria-fungi stacked plot combination
Bacteria-fungi correlation heat map
Bacteria-fungi correlation circos diagram |
| Environmental factor correlation analysis |
At the level of environmental factor correlation, comparative analysis of bacterial-environmental factors and fungal-environmental factors is carried out in terms of species diversity, OTU levels and function. We can obtain the characteristics of the association of bacteria and fungi with environmental factors; we can also compare the similarities and differences in the response of bacteria and fungi to environmental changes. |
Combined heat map-network diagram |
Delivery Content
Creative Proteomics will provide you with a detailed report, including:
- Related analysis software and parameters used
-
Graphs obtained from the integrated analysis
Why Choose Us?
- Professional bioinformatics analysis. Creative Proteomics has a strong bioinformatics team, which can meet various in-depth data analysis needs of customers, and can also provide integrated analysis services with other omics.
- One-stop service. Customers only need to provide samples, and Creative Proteomics will complete the full-service process from sample preparation, library preparation, high-throughput sequencing / Mass detection to bioinformatics analysis, as well as integrated analysis of multi-omics.
- Tailored and personalized analysis content is available for special projects.
Service Process
Creative Proteomics relies on advanced platforms and cutting-edge technologies to provide omics services to customers around the world, and provide accurate and detailed analysis reports. In addition, we also provide multi-omics integrated analysis services. If you want to know more, please contact us, Creative Proteomics can be trusted.
For Research Use Only.
