Why Do Integrative Analysis of PTM Omics and Metabolomics?

Post-translationally modified proteins can regulate cellular biological processes and affect metabolic changes in the body. PTM proteins that affect metabolism include not only PTM transcription factors, but also PTM metabolic enzymes. The metabolome is the overall level of small molecules (often called metabolites) within a cell, tissue or organism. Therefore, the integrated analysis of post-translational modification omics and metabolomics to compare their expression similarities and differences is beneficial to analyze the metabolic mechanism of organisms from different levels, and to explore differentially modified proteins, metabolites, and important pathways and related genes involved in them, so as to further in-depth research.

Our Integrative Analysis Services of PTM Omics and Metabolomics

Creative Proteomics uses mass spectrometry platform combined with nanoliter chromatography to provide post-translational modification identification services such as phosphorylation / glycosylation / ubiquitination / acetylation / methylation / disulfide bond / nitrosylation, as well as targets for a variety of samples targeted and untargeted metabolomic analysis services. It can also be integrated with customizable bioinformatics analysis methods to provide mass spectrometry-based post-translationally modified proteome and metabolome integration analysis services for the majority of scientific researchers to screen key post-translationally modified proteins / metabolites / metabolic pathway from massive data. Analyze the development of biological system processes, illustrate the complexity and integrity of biological processes, and provide powerful insights into the mechanisms of complex life activities.

• Protein PTMs Analysis
• Untargeted Metabolomics

Bioinformatics Analysis

Resolved Scientific Questions

• The similarities and differences of expression patterns of protein post-translational modifications and metabolites were compared to reveal their changing trends at different levels after biological treatment.
• Screen the important pathways that differentially modified proteins and metabolites are involved in, and reveal their potential functions in related biological changes.
• To analyze the regulatory relationship between protein post-translational modification and metabolites, and to describe the potential regulatory mechanism between protein post-translational modification and metabolites.

Delivery Content

Creative Proteomics will provide you with a detailed technical report, including:

• Experimental procedure (LC-MS/MS)
• Mass spectrum picture
• Raw omics data
• Related analysis software and parameters used
• Graphs obtained from the integrated analysis

Why Choose Us?

• Complete and advanced platform. Creative Proteomics has an advanced experimental platform that supports transcriptome / genome / microbiome sequencing and metabolome / proteome / lipidome detection, etc., and we have many successful project experiences.
• One-stop service. Customers only need to provide samples, and Creative Proteomics will complete the full-service process from sample preparation, library preparation, sequencing / detection to bioinformatics analysis, as well as integrated analysis of multi-omics.
• Professional bioinformatics analysis. Creative Proteomics has a strong bioinformatics team, which can meet various in-depth data analysis needs of customers, and can also provide integrated analysis services with other omics.

Creative Proteomics relies on advanced platforms and cutting-edge technologies to provide omics services to customers around the world, and provide accurate and detailed analysis reports. In addition, we also provide multi-omics integrated analysis services. You can discuss with our technical engineers to customize solutions or build new methods to meet your specific needs. If you have any questions, you can tell us through the inquiry form, and our technicians will communicate with you. Please don't hesitate to contact us, Creative Proteomics can be trusted.